Nitrofurantoin: An Alternative Therapy for Uncomplicated Cystitis in the Era of Antimicrobial Resistance
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منابع مشابه
Isolation of fluoroquinolone-resistant rectal Escherichia coli after treatment of acute uncomplicated cystitis.
OBJECTIVES Given increasing rates of co-trimoxazole resistance among uropathogens causing acute uncomplicated cystitis, fluoroquinolones, nitrofurantoin and fosfomycin are often considered as alternative empirical therapy. The choice between these drugs should depend in part on whether they are associated with the isolation of drug-resistant microbial flora. We conducted a randomized treatment ...
متن کاملNitrofurantoin, an Excellent Empiric Choice for Outpatient Cystitis.
We read the letter from Cortes-Penfield and Trautner (1) and thank them for their interest in our recent paper (2). In our paper, we demonstrated increasing resistance of Escherichia coli to ciprofloxacin and trimethoprim-sulfamethoxazole (TMP-SMX) in urinary isolates obtained from adult female outpatients, with the isolates retaining high levels of susceptibility to nitrofurantoin. Using our r...
متن کاملChoice of antibiotic for empirical therapy of acute cystitis in a setting of high antimicrobial resistance.
BACKGROUND A high prevalence of antimicrobial resistance among urinary isolates in the Garhwal region of Uttaranchal. AIMS To identify the most appropriate antibiotic for empirical treatment of community-acquired acute cystitis on the basis of local antimicrobial sensitivity profile. SETTINGS AND DESIGN A prospective clinico-microbiological study including all clinically diagnosed patients ...
متن کاملLow Concordance With Guidelines for Treatment of Acute Cystitis in Primary Care
Background. The updated 2010 Infectious Diseases Society of America guidelines recommended 3 first-line therapies for uncomplicated cystitis: nitrofurantoin, trimethoprim-sulfamethoxazole (TMP-SMX), and fosfomycin, while fluoroquinolones (FQs) remained as second-line agents. We assessed guideline concordance for antibiotic choice and treatment duration after introduction of the updated guideli...
متن کاملHow efficient can we treat presumed acute uncomplicated lower urinary tract infection in women with 3-day antibiotic in the Accident & Emergency Department?
Introduction: Urinary tract infection is a common problem in females encountered in the Accident & Emergency Department. The increasing prevalence of Escherichia coli and other urine isolates resistant to trimethoprim-sulfamethoxazole and ampicillin enhances the use of nitrofurantoin as the first line therapy. A guideline of 3-day antibiotic in presumed uncomplicated cystitis has been proved to...
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تاریخ انتشار 2011